Mac and Cheese Meatloaf

Mac and Cheese Meatloaf is a comforting, hearty casserole that combines a savory meatloaf base with creamy, cheesy macaroni, all topped with a golden, melty cheese layer. This fusion dish offers the best of both worlds: rich, flavorful meat and indulgent mac and cheese, creating a family-friendly meal that’s perfect for weeknights or gatherings.

Why You’ll Love This Recipe

Double Comfort – Combines classic meatloaf with creamy mac and cheese for maximum satisfaction.
Crowd-Pleasing – Perfect for family dinners, potlucks, or special occasions.
Hearty and Filling – Packed with protein and carbohydrates for a complete meal.
Flavor-Packed – Barbecue sauce, ketchup, and seasonings create a rich, savory base.
Cheesy Goodness – A melty cheese topping adds visual appeal and indulgence.
Easy Assembly – Prepares in layers for a straightforward casserole-style dish.

Ingredients You’ll Need

1 cup ketchup – Adds tanginess and moisture to the meatloaf.
1 cup Sweet Baby Ray’s Hickory & Brown Sugar BBQ sauce – Enhances flavor and caramelization.
2 lbs lean ground beef – Forms the protein-rich meatloaf base.
30 Ritz Crackers, crushed – Acts as a binder and adds subtle buttery flavor.
2 oz Lipton onion soup mix – Infuses the meat with savory depth.
2 eggs – Helps bind the meatloaf together.
3 cups macaroni noodles – Provides the classic mac and cheese base.
2 cups milk – Combines with cheese soup to create creamy sauce.
10.5 oz condensed cheddar cheese soup – Adds richness and smooth texture.
1 tsp salt – Enhances flavor throughout the dish.
1 tsp pepper – Provides subtle seasoning and balance.
1 tbsp garlic powder – Adds aromatic depth.
1 tbsp onion powder – Boosts savory flavor.
4 cups shredded mozzarella and cheddar cheese blend – For creamy mac and cheese and a melty topping.

Step-by-Step Instructions

Preheat and Prepare Dish – Heat oven to 350°F (175°C) and grease a 9×13-inch baking dish.
Mix Ketchup and BBQ Sauce – Combine in a small bowl and set aside for layering.
Prepare the Meatloaf Base – In a large bowl, mix ground beef, crushed crackers, onion soup mix, eggs, and ½ cup of ketchup/BBQ sauce mixture. Press evenly into the baking dish. Spread remaining sauce on top.
Bake the Meatloaf – Bake for 30 minutes to set the base and begin caramelization.
Cook the Macaroni – Prepare noodles according to package directions, drain, and set aside.
Make the Cheese Sauce – Whisk milk and cheddar cheese soup together in a large bowl. Add salt, pepper, garlic powder, and onion powder. Stir in cooked macaroni and 2 cups shredded cheese.
Layer Mac and Cheese – Remove meatloaf from oven. Pour mac and cheese mixture over meatloaf, spreading evenly. Sprinkle remaining cheese on top.
Finish Baking – Bake an additional 17–20 minutes until cheese melts and begins to brown. Let rest a few minutes before serving.

Recipe Notes & Tips

Rest Before Serving – Allows casserole to set, making it easier to slice.
Cheese Variety – Mix mozzarella with cheddar for optimal melt and flavor.
Season to Taste – Adjust garlic, onion, and pepper levels for personal preference.
Binder Options – Crushed crackers can be swapped with breadcrumbs if desired.
Serving Suggestion – Pair with a simple green salad for balance.

Nutritional Information

Prep Time: 20 minutes
Cook Time: 50 minutes
Total Time: 70 minutes
Servings: 8
Calories: ~600 per serving
Total Fat: 35 g
Total Carbohydrate: 40 g
Protein: 35 g

Perfect Pairings

Steamed vegetables – Broccoli or green beans add freshness and crunch.
Garlic bread – Complements cheesy flavors and adds texture.
Coleslaw – Adds a refreshing, tangy contrast.
Crisp white wine or iced tea – Balances richness with acidity or refreshment.

Ideal Occasions

Family dinners – Hearty enough to satisfy adults and kids alike.
Potlucks – Easy to transport and sure to please a crowd.
Comfort food nights – Rich, cheesy, and satisfying for cold evenings.
Special gatherings – Offers an elevated twist on classic comfort foods.

Storage & Serving Tips

Refrigeration – Store leftovers in an airtight container for up to 3 days.
Reheating – Warm in the oven at 175°C to maintain texture.
Freezing – Can be frozen before baking; bake directly from frozen with extra time.
Serve Hot – Ensures cheese stays melty and meatloaf tender.

Creative Variations to Try

Spicy Kick – Add hot sauce or cayenne to the meatloaf mixture.
Vegetable Boost – Mix in diced bell peppers or spinach into the mac and cheese.
Cheese Medley – Use Gouda, Fontina, or pepper jack for different flavors.
BBQ Twist – Swap classic BBQ sauce for a smoky chipotle version.

Troubleshooting Common Issues

Meatloaf Falls Apart – Ensure eggs and crackers are well-mixed as binders.
Cheese Not Melting – Ensure mac and cheese is fully combined before baking.
Casserole Too Wet – Drain macaroni slightly before mixing with cheese sauce.
Uneven Baking – Use a 9×13-inch dish for even heat distribution.

Why This Recipe Works

This casserole combines the protein-rich meatloaf with creamy, cheesy macaroni, creating layers of flavor and texture. The ketchup and barbecue sauce add moisture and tang, while the cheese sauce binds everything together. Baking first the meatloaf and then layering the macaroni ensures even cooking and prevents sogginess. With roughly 600 calories per serving, it’s a hearty, satisfying meal that delivers both comfort and flavor in every bite.

Final Thoughts

Mac and Cheese Meatloaf is the ultimate comfort food, blending creamy macaroni and cheese with a savory meatloaf base. It’s perfect for family dinners, potlucks, or any occasion where hearty, flavorful food is desired. Easy to customize and always satisfying, this casserole is a delicious twist on two classic favorites, offering both richness and comfort in one dish.